eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
Current issue Archive Manuscripts accepted About the journal Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
3/2019
vol. 36
 
Share:
Share:
abstract:
Original paper

Assessment of autonomic nervous system functions and cardiac rhythms in patients using isotretinoin

Halil Ay
1
,
Mustafa Aksoy
2
,
Fatih Güngören
3

  1. Department of Neurology, Harran University, Şanlıurfa, Turkey
  2. Department of Dermatology, Harran University, Şanlıurfa, Turkey
  3. Department of Cardiology, Harran University, Şanlıurfa, Turkey
Adv Dermatol Allergol 2019; XXXVI (3): 291–294
Online publish date: 2018/06/29
View full text Get citation
 
Aim
The aim of the study was to analyze the potential effects of isotretinoin, frequently used in the treatment of acne vulgaris these days.

Material and methods
For this purpose, we used the methods of sympathetic skin response (SSR) electrophysiological analysis and electrocardiographic (ECG) analysis in patients using isotretinoin. Thirty patients who were diagnosed with acne vulgaris and treated with oral isotretinoin with a dose of 0.5 mg/kg for at least 1 month were included in the study. In all patients ECG scanning and SSR analysis were performed both before treatment and 1 month after the start of treatment.

Conclusions
This study is very important because SSR results show that increasing the existing sympathetic activity in acne vulgaris after isotretinoin usage could explain the exacerbation in acne lesions for the first month, and according to the ECG results the medication did not cause cardiac side effects.

keywords:

isotretinoin, sympathetic skin response, acne vulgaris

Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.