eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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4/2009
vol. 34
 
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abstract:

Experimental immunology
Non-specific humoral immunity in rabbits infected with the selected German strains of the RHD (rabbit haemorrhagic disease) virus

Paulina Niedźwiedzka-Rystwej
,
Wiesław Deptuła

Centr Eur J Immunol 2009; 34 (4): 218-221
Online publish date: 2009/12/30
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The study aimed to analyse selected parameters of non-specific humoral immunity (myeloperoxidase - MPO activity, as well as lysozyme - LZM concentration and activity) in rabbits infected with three German (Hagenow, Frankfurt, Triptis) strains of the RHD virus with different biological properties. The results of the study showed that biological properties (i.e. different reactivity in the HA test and formation of antigen variant), have impact on the analysed non-specific humoral immunity factors, as antigen variant Triptis causing high mortality at a very short time was the most immunogenic strain, while the strain with variable haemagglutination capacity Hagenow proved to be the least immunogenic strain.
keywords:

RHD virus, haemagglutination capacity, antigenic variant
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