eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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3/2010
vol. 35
 
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abstract:

Experimental immunology
Some immunotropic effects of Rhaponticum carthamoides

Ewa Skopińska-Różewska
,
Aleksander Wasiutyński
,
Krzysztof Pastewka
,
Beata Białas-Chromiec
,
Małgorzata Bychawska
,
Anna Geszprych
,
Zenon Węglarz

(Centr Eur J Immunol 2010; 35 (3): 138-141)
Online publish date: 2010/10/05
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Rhaponticum (leuzea) carthamoides (Compositae) has been used for many years in traditional Chinese, Tibetan, Mongol and Russian medicine as an adaptogenic and anabolic remedy. Some other biological effects of this plant were also described. This paper presents an influence of hydroalcoholic extract of this plant on some aspects of cellular and humoral immunity in mice. Additionally, the effect of this extract on the neovascular reaction induced in mice skin after grafting of cells isolated from human kidney cancer was evaluated. Oral administration of the extract for 5 days, in daily doses of 0.25 mg per mouse, resulted in an increase of chemokinetic activity of splenic lymphocytes and anti-SRBC antibody production. No influence of the extract on metabolic activity of mice blood granulocytes nor on the angiogenic activity of human kidney cancer cells were observed.
keywords:

Rhaponticum carthamoides, Leuzea, mice, immunity, human cancer, angiogenesis
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